Biochemistry of Selenium

Inhaltsverzeichnis

• 1. Forms of Selenium.
• 1.1 Low Molecular-Weight Compounds.
• 1.2 Macromolecular Forms of Selenium.
• 11.11 References.
• 2. Selenium Deficiency Diseases in Animals.
• 2.1 Introduction.
• 2.2 Dietary Liver Necrosis and Factor 3.
• 2.3 Nutritional Muscular Dystrophy.
• 2.4 Exudative Diathesis.
• 2.5 Pancreatic Degeneration.
• 2.6 Mulberry Heart Disease.
• 2.7 Reproductive Problems.
• 2.8 Myopathy of the Gizzard.
• 2.9 Growth.
• 2.10 Selenium—Responsive Unthriftiness of Sheep and Cattle.
• 2.11 Periodontal Disease of Ewes.
• 2.12 Encephalomalacia.
• 3. Metabolism of Selenium.
• 3.1 Absorption.
• 3.2 Placental Transfer.
• 3.3 Mechanism of the Antioxidant Action of Selenium.
• 3.4 Effect of Paraquat.
• 3.5 Effect on Cytochrome P-450.
• 3.6 Selenium and Hepatic Heme Metabolism.
• 4. Comparative Metabolism and Biochemistry of Selenium and Sulphur.
• 4.1 Introduction.
• 4.2 Comparative Metabolism of Selenium and Sulphur.
• 4.3 Comparative Biochemistry of Selenium and Sulphur.
• 5. Biological Interactions of Selenium with Other Substances.
• 5.1 Cadmium.
• 5.2 Arsenic.
• 5.3 Copper.
• 5.4 Silver.
• 5.5 Cobalt.
• 5.6 Manganese.
• 5.7 Lead.
• 5.8 Mercury.
• 5.9 Thallium.
• 5.10 Tellurium.
• 5.11 Vanadium.
• 5.12 Bismuth.
• 5.13 Other Substances.
• 6. Environmental Occurrence of Selenium.
• 6.1 Geochemistry of Selenium.
• 6.2 Soil Selenium.
• 6.3 Uptake and Concentration of Trace Elements in the Roots, Stems, and Leaves of Plants.
• 6.4 Forage Selenium.
• 6.5 Selenium in Water.
• 6.6 Selenium in Food.
• 6.7 Intakes and Recommended Daily Allowance in Humans.
• 6.8 Regulations in Regard to Animal Diets.
• 7. Toxicity of Selenium.
• 7.1 Introduction.
• 7.2 Industrial Medical Aspects.
• 8. Selenium in Health and Disease.
• 8.1 Selenium and Cancer.
• 8.2 Selenium and Mutagenesis.
• 8.3 Selenium and Immunity.
• 8.4 Selenium and Dental Caries.
• 8.5 The Anti-Inflammatory Properties of Selenium.
• 8.6 Selenium and Heart Disease.
• 8.7 Selenium and Aging.
• 8.8 Cystic Fibrosis.
• 8.9 Multiple Sclerosis.
• 8.10 Cataracts.
• 8.11 Other Diseases.
• 8.12 Radioselenium as a Diagnostic Agent.
• 9. Synthetic Forms of Selenium and Their Chemotherapeutic Uses.
• 9.1 Anti-Infective Agents.
• 9.2 Antifungal Agents.
• 9.3 Antiparasitic Agents.
• 9.4 Compounds Affecting the Central Nervous System.
• 9.5 Compounds that Affect the Autonomic Nervous System.
• 9.6 Compounds that Affect the Circulatory System.
• 9.7 Anti-Inflammatory Compounds.
• 9.8 Antihistamines.
• 9.9 Anticancer Agents.
• 9.10 Antiradiation Agents.
• 9.11 Steroids.
• 9.12 Selenocoenzyme A.
• 9.13 Selenium-Containing Carbohydrates.
• 9.14 Seleno-Amino Acids.
• 10. Analytical Methods of Selenium Determination.
• 10.1 Introduction.
• 10.2 Sample Preparation and Storage.
• 10.3 Destructive Analysis.
• 10.4 Nondestructive Analysis.
• References.