Mitochondrial DNA | Methods and Protocols | ISBN 9781071629215

Mitochondrial DNA

Methods and Protocols

herausgegeben von Thomas J. Nicholls, Jay P. Uhler und Maria Falkenberg
Mitwirkende
Herausgegeben vonThomas J. Nicholls
Herausgegeben vonJay P. Uhler
Herausgegeben vonMaria Falkenberg
Buchcover Mitochondrial DNA  | EAN 9781071629215 | ISBN 1-0716-2921-2 | ISBN 978-1-0716-2921-5

Mitochondrial DNA

Methods and Protocols

herausgegeben von Thomas J. Nicholls, Jay P. Uhler und Maria Falkenberg
Mitwirkende
Herausgegeben vonThomas J. Nicholls
Herausgegeben vonJay P. Uhler
Herausgegeben vonMaria Falkenberg

This volume compiles a comprehensive range of methods to study key aspects of mitochondrial DNA including nucleoid structure and packaging, replication, genome integrity, and disease. Chapters are organized into eight methodological sections that cover in vitro  and  in vivo  methods, including for mtDNA isolation, visualization, deep sequencing,  gene editing, and diagnostic aspects of mtDNA disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge,  Mitochondrial DNA: Methods and Protocols aims to be useful and informative for researchers and clinicians with an interest in mitochondrial DNA.