Opioid Peptides and Blood Pressure Control

Inhaltsverzeichnis

Endogenous Opioids and Cardiovascular Regulation: Introduction.- Anatomy.- Distribution of Opioid Peptides Functionally Related to the Cardiovascular System.- Studies on Enkephalinergic Mechanisms in Cardiovascular Centers of the Medulla Oblongata of the Rat and their Interactions with Centrally Administered Neuropeptide Y.- Multiplicity of Opioidergic Pathways Related to Cardiovascular Innervation: Differential Contribution of All Three Opioid Precursors.- Physiology.- Opioids, Opiate Receptors, and Central Cardiovascular Regulation.- Adrenergic Opioid Interaction in the Brain Stem: Role in Cardiovascular Regulation.- Influence of the Opioid System on Sympathetic Activity and the Renin-Aldosterone System in Healthy Males.- Role of Leu-morphin, an Opioid Peptide, in the Central Regulation of Fluid Balance and Blood Pressure in Rats.- Endogenous Opioids in the Dorsal Vagal Complex and Resting Cardiovascular Function in the Anesthetized Rat.- Influence of Opiate Peptides on Blood Pressure Regulation and on Hypothalamic Blood Flow.- Opioid Peptides in Human Adrenal Medulla: Their Role in the Modulation of Catecholamine Secretion.- Cardiovascular Effects of Neuropeptide Y in the Caudal Ventrolateral Medulla.- Plasma Met-enkephalin and Cardiovascular Responses to Stress.- Pharmacology.- Opioid Receptors in the Sympathetic Supply to Blood Vessels and the Heart.- Interactions of Opioid Peptides and Adrenergic Agents in the Regulation of Blood Pressure.- Effect of Opiate Receptor Blockade on the Cardiovascular and Plasma Noradrenaline Response to Intravenous Tyramine in Man.- Effects of Mu- and Delta-Opiate Receptor Agonists on Systemic and Regional Hemodynamics in Conscious Rats.- Retardment of Development of Hypertension in the Spontaneously Hypertensive Rat by Long-Term Kappa-Opioid Receptor Antagonism.- Naltrexone Inhibits Alpha-Methydopa-Induced Hypotension in a Dose-Dependent Manner.- Effects of 17-alpha-estradiol, a Possible Endogenous Opiate Antagonist, on Cardiovascular Responses in Conscious Unrestrained Rats.- Opioid Receptor Types at Noradrenergic Neurons and their Roles in Blood Pressure Regulation.- Effect of Opioids on Plasma Levels of Immunoreactive Atrial Natriuretic Factor.- Production by Systemic Enkephalin of Hemodynamic Effects by Afferent Modulation of Autonomic Nervous System Tone.- Pathophysiology and Clinical Aspects.- Endogenous Opioids in the Pathophysiology of Shock: Sites of Action, Autonomic Involvement, and Receptor Interactions.- Endogenous Opioids and Blood Pressure in Man.- Effects of Hemorrhagic Shock on Plasma Met-enkephalin, Vasopressin, Catecholamines, and Cardiovascular Functions in Intact and Adrenalectomized Dogs.- Effect of Hypertension on the Response of Plasma Beta-Endorphin to the Cold Pressor Test.- Normalization by Clonidine of Reduced Plasma Beta-endorphin and Leu-enkephalin Concentrations and Elevated Blood Pressure in Young Patients with Mild Essential Hypertension.- Role of Opioids in the Pathophysiology of Hypertension.- Effect of Low Dosage of Naloxone on Clonidine-Induced Changes in Blood Pressure, Catecholamines, Renin, and Aldosterone in Essential Hypertension.- Effect of Lisinopril on Circulating Neuropeptides in Essential Hypertensive Patients.- Endogenous Opioids and Reversal of Renovascular Hypertension.- Comparison of Pain Threshold as Assessed by Tooth Pulp Stimulation in Normotensives with Different Hypertensive Hereditary Backgrounds and in Borderline and Established Hypertensives.