Skeletal Reconstruction and Bioimplantation

This book presents new information on the use of demineralized bone matrix and osteoinductive proteins (bone morphogenetic proteins) as bioactive grafts in reconstructive surgery (orthopedic and maxillofacial surgery), and details the measurement of osteoinductivity in animal experiments and in clinical use. The biochemical mechanisms and clinical implications for skeletal reconstruction and bioimplantation are presented in three sections: (1) Documentation of Osteoinductivity, (2) Bioactive Delivery Systems, and (3) Genetics and Osteoinduction. The use of osteoinductive implants in bone transplantation should become standard practice, and Skeletal Reconstruction and Bioimplantation will be considered among the pioneering works in the field.