Marihuana | Chemistry, Biochemistry, and Cellular Effects | ISBN 9783642516269


Chemistry, Biochemistry, and Cellular Effects

bearbeitet von G.G. Nahas
Buchcover ISBN


Chemistry, Biochemistry, and Cellular Effects

bearbeitet von G.G. Nahas


I Marihuana Chemistry.- Detection and Identification of Cannabinoids and of Their Metabolites.- 1 Cannabinoid Chemistry: An Overview.- 2 Detection and Identification of Compounds in Cannabis.- 3 Pyrolysis of Cannabinoids.- 4 Some Aspects of Cannabis Smoke Chemistry.- 5 Identification of Cannabinoids and Metabolites in Biological Materials by Combined Gas-Liquid Chromatography-Mass Spectrometry.- 6 Comparison of Various Solvent Extractions for the Chromatographic Analysis of A9- Tetrahydrocannabinol and Its Metabolites.- 7 Radioimmunoassay of Cannabis Products in Blood and Urine.- 8 Mass Fragmentographic Assays for the Cannabinoids and Their Metabolites.- 9 Examination of the Metabolites of ?1-Tetrahydrocannabinol in Mouse Liver, Heart, and Lung by Combined Gas Chromatography and Mass Spectrometry.- 10 Identification and Quantification of Cannabinoids in Urine by Gallium Chelate Formation.- 11 Forensic, Metabolic, and Autoradiographic Studies of ?8- and ?9-Tetrahydrocannabinol.- Kinetics and Biotransformation.- 12 Cannabinoids: Metabolites Hydroxylated in the Pentyl Side Chain.- 13 Identification of Hydroxylated Cannabinoids by PMR and Mass Spectroscopy.- 14 The Pharmacokinetics of ?9-Tetrahydrocannabinol and Its Metabolites: Importance and Relationship in Developing Methods for Detecting Cannabis in Biologic Fluids.- 15 Rate of Penetration of ?9-Tetrahydrocannabinol and 11-Hydroxy-?9-Tetrahydrocannabinol to the Brain of Mice.- 16 Changes in the Metabolism of ?9-Tetrahydrocannabinol Caused by Other Cannabis Constituents.- II Marihuana: Biochemical and Cellular Effects.- Effects on Isolated Cell Systems.- 17 The Influence of Marihuana on Eukaryote Cell Growth and Development.- 18 Inhibition of Proliferation and Differentiation of Dictyostelium Discoideum Amoebae by Tetrahydrocannabinol and Cannabinol.- 19 ?9-Tetrahydrocannabinol: Effect on Macromolecular Synthesis in Human and Other Mammalian Cells.- 20 In Vitro Inhibition of Protein and Nucleic Acid Synthesis in Rat Testicular Tissue by Cannabinoids.- 21 Cytological and Cytochemical Effects of Whole Smoke and of the Gas Vapor Phase from Marihuana Cigarettes on Growth and DNA Metabolism of Cultured Mammalian Cells.- 22 Effects of ?8-Tetrahydrocannabinol, ?9-Tetrahydrocannabinol, and Crude Marihuana on Human Cells in Tissue Culture.- 23 Errors of Chromosome Segregation Induced by Olivetol, a Compound with the Structure of C-ring Common to Cannabinoids: Formation of Bridges and Multipolar Divisions.- 24 Effect of ?1-Tetrahydrocannabinol on Red Blood Cell Membranes and on Alveolar Macrophages.- 25 Cannabinoids: Effects on Lysosomes and Lymphocytes.- 26 Inhibitory Effects of ?9-Tetrahydrocannabinol on Nucleic Acid Synthesis and Proteins in Cultured Lymphocytes.- 27 Cellular Alterations Induced in Vitro by ?1-Tetrahydrocannabinol: Effects on Cell Proliferation, Nucleic Acids, Plasma Cell Membrane ATPase, and Adenylate Cyclase.- 28 Cannabinoids and Neoplastic Growth.- Interactions with Neurotransmitters.- 29 A Comparison of the Subcellular Distribution of Cannabinoids in the Brains of Tolerant and Nontolerant Dogs, Rats, and Mice After Injecting Radiolabeled ?9-Tetrahydrocannabinol.- 30 Sites of Neurochemical Action of ?9-Tetrahydrocannabinol Interaction with Reserpine.- 31 Effects of ?9-Tetrahydrocannabinol on the Homosynaptic Depression in the Spinal Monosynaptic Pathway: Implications for Transmitter Dynamics in the Primary Afferents.- 32 Effects of Cannabinoids on Isolated Smooth Muscle Preparations.- 33 Effects of ?9-Tetrahydrocannabinol and Cannabinol on Rat Brain Acetylcholine.- 34 Cannabinoids and the Inhibition of Prostaglandin Synthesis.- 35 Effects of Cannabinol Derivatives on Blood Pressure, Body Weight, Pituitary-Adrenal Function and Mitochondrial Respiration in the Rat.- Organic and Developmental Effects.- 36 The Immune Response and Marihuana.- 37 Teratologic Effects of Cannabis Extracts in Rabbits: A Preliminary Study.- 38 Alteration of ?9-Tetrahydrocannabinol-Induced Prenatal Toxicity by Phenobarbital and SKF-525A.- 39 Pharmacogenetic Studies on Cannabis and Narcotics: Effects of ?1-Tetrahydrocannabinol and Morphine in Developing Mice.- 40 Permanent Learning Impairment After Chronic Heavy Exposure to Cannabis or Ethanol in the Rat.- 41 Cannabis Sativa Derivatives: Effects on Brain Function of Monkeys.- 42 Marihuana’s Effects on Human Gonadal Functions.- 43 Cellular Effects of Chronic Cannabis Use in Man.- Concluding Summary.


556 Seiten
Softcover reprint of the original 1st ed. 1976
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23,5 x 15,5 cm, 884 gr
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