Geschwülste · Tumors II

Inhaltsverzeichnis

• — Contents.
• DNS-haltige onkogene Viren und Tumorgenese.
• I. Allgemeine Beschreibung von Polyoma und SV40 Virus.
• II. Allgemeine Beschreibung der Papilloma Viren.
• III. Adeno SV40 Hybridviren.
• IV. Allgemeine Beschreibung der Adenoviren.
• V. Allgemeine Beschreibung der Herpesviren.
• Ausblick.
• Literatur.
• RNA Tumor Virus Oncogenesis.
• I. Introduction.
• II. General Properties of RNA Tumor Viruses.
• III. Replication of RNA Tumor Viruses in Host Cells.
• IV. Factors Influencing the Neoplastic Transformation of Cells by RNA Tumor Viruses.
• V. Involvement of RNA Tumor Viruses in Human Cancer?.
• References.
• Murine Virus-Leukämien.
• I. Einleitung.
• II. Pathobiologie der virusinduzierten murinen Leukämien.
• III. Infektiosität und Übertragungsweisen muriner Leukämieviren.
• IV. Feinstruktur und Bildungsweise der Mäuseleukämie-Viren und ihre Verteilung im leukämischen und präleukämischen Tier.
• V. Murine Leukämieviren in vitro.
• VI. Die Immunologie virusinduzierter Leukämien der Maus.
• VII. Biochemie der murinen Leukämieviren.
• Potential Viral Etiology of Human Tumors.
• I: General Aspects.
• II: Possible Virus-Induced Human Neoplasms.
• III.
• Summary.
• Molecular Mechanisms of Chemical Carcinogenesis.
• 1. Introduction.
• 2. Nitrosamines.
• 3. Cycasin; Aliphatic Hydrazo, Azo and Azoxy Compounds; Triazenes.
• 4. Alkylating Agents and Ethionine. Possible Significance of Nucleic Acid Alkylation.
• 5. Aromatic Amines and Azo-Dyes.
• 6. 4-Nitroquinoline 1-Oxide.
• 7. Polycyclic Aromatic Hydrocarbons.
• 8. Aflatoxins.
• 9. Pyrrolizidine Alkaloids and Safrole.
• 10. Conclusions.
• Acknowledgements.
• Chemische Carcinogene in der menschlichen Umwelt.
• 1. Vorbemerkung.
• 2. Einleitung.
• 3. Umweltcarcinogene.
• Pharmacodynamic Mechanism inCarcinogenesis.
• II. Cell Cancerization as an Unusual Pharmacodynamic Phenomenon.
• III. Summation Action in Carcinogenesis.
• IV. Experimental Syncarcinogenesis.
• V. Anticarcinogenesis.
• Cocarcinogens and Cocarcinogenesis.
• 1. Exogenous Cocarcinogens.
• 2. Endogenous Cocarcinogens.
• 3. Cocarcinogenesis as a Tool for the Investigation of the Biological and Biochemical (Molecular) Mechanisms of Carcinogenesis.
• 4. Note on Synergistic Processes in Carcinogenesis.
• Conclusion.
• Chromosomal Alterations and Development of Experimental Tumors.
• II. Historical Review of Cytogenetic Studies of Tumor Cells.
• III. Karyotype in the Early Stages of Tumor Development and Primary Tumors.
• IV. Alteration of Stemline Karyotype in the Course of Serial Transplantations.
• V. Chromosome Condition and Invasiveness of Tumor Cells.
• VI. Change of Stemline Karyotype During in-vitro Cultivation.
• VII. Chromosome Change and Gene Action in Tumor Cells.
• VIII. Mutation and Selection for Karyotype Alteration in Tumor Stemline Cells.
• IX. Aging of Tumor Stemline Cells and Karyotype Alteration.
• Acknowledgments.
• Namenverzeichnis — Author Index.
• Sachverzeichnis — Subject Index.