Trafficking Inside Cells

Inhaltsverzeichnis

• Compartments and Pathways.
• Overview of Intracellular Compartments and Trafficking Pathways.
• How We Study Protein Transport.
• The Golgi Apparatus.
• The Endocytic Pathway.
• Regulated Secretion.
• Mechanisms.
• Overview of Protein Trafficking Mechanisms.
• Entry into the Endoplasmic Reticulum: Protein Translocation, Folding and Quality Control.
• COP-Mediated Vesicle Transport.
• Clathrin-Mediated Endocytosis.
• Biogenesis of Dense-Core Secretory Granules.
• Lipid-Dependent Membrane Remodelling in Protein Trafficking.
• Carrier Motility.
• Tethering Factors.
• Intracellular Membrane Fusion.
• Regulation and Coordination with Other Cellular Processes.
• Regulation and Coordination of Intracellular Trafficking: An Overview.
• Regulation of Protein Trafficking by GTP-Binding Proteins.
• Posttranslational Control of Protein Trafficking in the Post-Golgi Secretory and Endocytic Pathway.
• Actin Doesn’t Do the Locomotion: Secretion Drives Cell Polarization.
• Intracellular Trafficking and Signaling: The Role of Endocytic Rab GTPase.
• The Exocytic Pathway and Development.