Synaptic Modulators | ISBN 9781468431797

Synaptic Modulators

herausgegeben von Leslie Iversen
Buchcover Synaptic Modulators  | EAN 9781468431797 | ISBN 1-4684-3179-X | ISBN 978-1-4684-3179-7

Synaptic Modulators

herausgegeben von Leslie Iversen

Inhaltsverzeichnis

  • 1 Effects of Drugs on Energy Metabolism of the Brain and on Cerebral Transport.
  • 1. Introduction.
  • 2. Drugs and Brain Cell Energetics.
  • 3. Neurotropic Drugs Affecting Electron and Energy Transfer.
  • 4. Drugs and Brain Cell Permeabilities.
  • 5. Drugs Affecting Cerebral Biogenic Amine Levels.
  • 6. Ethanol.
  • 7. References.
  • 2 Role of Cyclic Nucleotides in the Nervous System.
  • 2. Enzymatic Formation, Degradation, and Action of Cyclic Nucleotides.
  • 3. Accumulation of Cyclic Nucleotides.
  • 4. Functional Roles of Cyclic Nucleotides.
  • 5. Conclusion.
  • 6. References.
  • 3 Purinergic Transmission.
  • 2. Distribution of Purinergic Nerves.
  • 3. Fine Structure and Histochemistry of Purinergic Nerves.
  • 4. Electrophysiology of Purinergic Transmission.
  • 5. Physiological Roles of Purinergic Nerves.
  • 6. Evidence that ATP is the Purinergic Nerve Transmitter.
  • 7. Pharmacology of Adenyl Compounds and Purinergic Transmission.
  • 8. Speculations on the Evolution and Development of Purinergic Nerves.
  • 9. Summary.
  • 10. References.
  • 4 Hypothalamic Hypophysiotropic Hormones.
  • 2. Hypophysiotropic Hormone Action.
  • 3. Thyrotropin Releasing Factor (TRF).
  • 4. Luteinizing Hormone Releasing Factor (LRF).
  • 5. Corticotropin Releasing Factor (CRF).
  • 6. Prolactin Release Inhibiting Factor (PIF).
  • 7. Growth Hormone Releasing Factor (GRF).
  • 8. Somatostatin-Somatotropin Release Inhibiting Factor (SRIF).
  • 9. References.
  • 5 Binding, Metabolism, and Action of Steroid Hormones in the Central Nervous System.
  • 2. Estrogens.
  • 3. Androgens.
  • 4. Glucocorticoids.
  • 5. Progestins.
  • 6. Conclusion.
  • 6 Opiate Receptor Mechanisms.
  • 2. Biochemical Identification of Opiate-Receptor Binding.
  • 3. Localization of the Opiate Receptor to Synaptic Membranes.
  • 4. Regional Distribution of Opiate-Receptor Binding.
  • 5. Effect of Destruction of Norepinephrine, Serotonin, Acetylcholine, and Dopamine Tracts on Opiate-Receptor Binding.
  • 6. Phylogenetic Distribution of the Opiate Receptor.
  • 7. Effect of Sodium on Opiate-Receptor Binding.
  • 8. Toward a Theory of Addiction.
  • Addendum to Chapter 2.