Eicosanoids

Inhaltsverzeichnis

• 1. Leukotriene A4 Hydrolase: A Key Enzyme in the Biosynthesis of Leukotriene B4.
• 2. Lipoxygenases of Mice and Men.
• 3. The Physiological and Therapeutic Significance of Separate Pathways for Prostaglandin Synthesis.
• 4. Assessment of Pharmacological Inhibition of PGH-Synthases in Man.
• 5. Metabolism of Eicosanoids in Mammalian Cells.
• 6. New Approach in Immunometric Assays.
• 7. Transcellular Biosynthesis of Arachidonic Acid Metabolites: From in Vitro Investigations to in Vivo Reality.
• 8. Polymorphonuclear-Endothelial Cell Interactions and the Control of Coronary Vasculature.
• 9. PGHS-2 Dependent Formation of 8-Epi PGF2? by Human Monocytes.
• 10. Platelet-Activating Factor Regulates Events at the Vascular Wall.
• 11. Studies of Isoprostane Biosynthesis in Man.
• 12. N-3 Fatty Acids. Antithromboxane Activity. Effects on Redox Status of Blood Cells.
• 13. Receptors and Second Messengers for cys-Leukotrienes.
• 14. Prostanoid Receptors: Classification, Characterisation and Therapeutic Relevance.
• 15. Microvascular Actions and Interactions of Eicosanoids and Histamine in Inflammation.
• 16. Leukotriene Antagonists and Synthetase Inhibitors; Clinical Applications in the Treatment of Bronchial Asthma.
• 17. PGI2 and Its Analogs: From Pharmacology to Therapeutic Applications.
• 18. Leukotriene Synthesis (FLAP) Inhibition: Biochemistry and Pharmacology of Bay X 1005.