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![]( "Buchcover ISBN 9781617372407")
From the reviews:
„This book describes in detail major advances in vaccine adjuvant discovery, design, development, and use. … fills a void in our knowledge of vaccine adjuvants, providing one authoritative text source for the latest information on this topic. The book meets the authors’ objectives superbly. … it could serve as a reference for students, residents, and practitioners, particularly in the fields of infectious diseases and immunology. … It will serve as a valuable reference for those interested in this field.“ (Archana NMI Chatterjee, Doody’s Review Service, July, 2006)
A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.
