“Recognized experts in the field describe the potential clinical impact of an emerging technology for the treatment of prostate cancer, focal therapy. … This is a very good reference for those who are contemplating including focal therapy for prostate cancer into their treatment paradigm and need a review of the contemporary issues.” (Costas D. Lallas, Doody's Book Reviews, May, 2015)
Technical Aspects of Focal Therapy in Localized Prostate Cancer
herausgegeben von Eric Barret und Matthieu DurandFocal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy.
These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity.
As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure.
Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists.
