Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis

Inhaltsverzeichnis

• 1 Introduction.
• 2 The Spectram of Inflammatory Demyelinating Diseases.
• 2.1 Experimental Models.
• 2.2 Human Diseases.
• 3 Allergic Encephalomyelitis in Humans.
• 4 The Pathology of Inflammatory Demyelinating Lesions.
• 4.1 Inflammatory Reaction.
• 4.2 Vascular Pathology.
• 4.3 Blood-Brain Barrier.
• 4.4 Demyelination and Myelin Degradation.
• 4.5 The Fate of Oligodendroglia.
• 4.6 Remyelination.
• 4.7 Sclerosis.
• 4.8 Axonal and Neuronal Pathology.
• 4.9 Meningeal Pathology.
• 4.10 Peripheral Nervous System Pathology.
• 4.11 Patterns of Plaque Growth.
• 4.12 Lesional Topography in the CNS.
• 4.13 The Variability of Inflammatory Demyelinating Lesions.
• 4.14 EAE as a Model of Human Inflammatory Demyelinating Diseases.
• 5 Immunopathogenetic Considerations.
• 5.1 Transfer Studies.
• 5.2 The Possible Role of Autoantigens in the Pathogenesis of Inflammatory Demyelinating Lesions.
• 5.3 Conclusions.
• 6 Addendum: Material and Methods — Models of Chronic EAE.
• 6.1 Material and Methods.
• 6.2 Factors Modifying the Development of Chronic EAE Models.
• 7 References.