Progress in Molecular and Subcellular Biology

Inhaltsverzeichnis

• Synthesis of Small Nuclear RNAs.
• 1 Introduction.
• 2 Two Classes of U snRNA Genes.
• 3 RNA Polymerases Transcribing U snRNA Genes.
• 4 Organization of U snRNA Genes.
• 5 Cis-Acting Elements in U snRNA Genes.
• 6 Interconversion of U snRNA Promoters.
• 7 Regulation of snRNA Synthesis.
• 8 Formation of Cap Structure in U snRNAs.
• 9 Summary.
• References.
• The DNA-Activated Protein Kinase, DNA-PK.
• 1 Nuclear Protein Kinases.
• 2 Nucleic Acid Effects on Protein Kinase Activity.
• 3 Detection of DNA-Stimulated Protein Phosphorylation in Cell Extracts.
• 4 Purification of DNA-PK from HeLa Cells.
• 5 Physical Characteristics of DNA-PK.
• 6 Subcellular Localization.
• 7 Phosphate Donor and Cofactor Requirements.
• 8 Effects of Inhibitors.
• 9 Substrate Specificity.
• 10 Effects of Polynucleotides.
• 11 Occurrence of DNA-PK in Other Cells.
• 12 Comparison with Other Nuclear Protein Kinases.
• 13 Conclusions and Future Directions.
• The Cytoskeleton During Early Development: Structural Transformation and Reorganization of RNA and Protein.
• 2 The Cytoskeleton in the Early Development of Chordates.
• 3 The Cytoskeleton in the Early Development of Nonchordates.
• 4 Conclusion.
• Developmental Regulations of Heat-Shock Protein Synthesis in Unstressed and Stressed Cells.
• 2 Expression of Heat-Shock Genes During Gametogenesis and Early Development in the Absence of Stress.
• 3 Heat-Shock Protein Synthesis in Differentiation Processes.
• 4 Deficient Heat-Shock Responses.
• 5 Concluding Remarks.
• The Interactions of Water and Proteins in Cellular Function.
• 2 The Cluster Model of Liquid Structure.
• 3 The Domain Model of Protein Structure.