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„[The] editors have succeeded admirably in inviting interestingauthors to assemble a handy overview of the most importantreactions and a number of concepts ... . The present monograph hasachieved the goal of covering truly interesting reactions andcatalysts.“ (Organic Chemistry Portal, May 2009)
„... this book has definite value and is strongly recommended forinclusion in both academic and industrial researchlibraries.“ (Angewandte Chemie, Intern. Edition, November 2007)
A compilation of recent advances and applications in asymmetriccatalysis
The field of asymmetric catalysis has grown rapidly and plays a keyrole in drug discovery and pharmaceuticals. New Frontiers inAsymmetric Catalysis gives readers a fundamental understanding ofthe concepts and applications of asymmetric catalysis reactions anddiscusses the latest developments and findings. With contributionsfrom preeminent scientists in their respective fields, itcovers:
* „Rational“ ligand design, which is critically dependent on thereaction type (reduction, oxidation, and C-C bond formation)
* Recent findings on activation of C-H bonds, C-C bonds, and smallmolecules (C=O, HCN, RN=C, and CO2) and the latest developments onC-C bond reorganization, such as metathesis
* Advances in „chirally economical“ non-linear phenomena, racemiccatalysis, and autocatalysis
* Some of the recent discoveries that have led to a renaissance inthe field of organocatalysis, including the development of chiralBrönstead acids and Lewis acidic metals bearing the conjugatebase of the Brönstead acids as the ligands and the chiralbi-functional acid/base catalysts
The book ends with a thought-provoking perspective on the future ofasymmetric catalysis that addresses both the challenges and theunlimited potential in this burgeoning field. This is anauthoritative, up-to-date reference for organic chemists inacademia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also anexcellent textbook for graduate students studying advanced organicchemistry or chemical synthesis.
The field of asymmetric catalysis has grown rapidly and plays a keyrole in drug discovery and pharmaceuticals. New Frontiers inAsymmetric Catalysis gives readers a fundamental understanding ofthe concepts and applications of asymmetric catalysis reactions anddiscusses the latest developments and findings. With contributionsfrom preeminent scientists in their respective fields, itcovers:
* „Rational“ ligand design, which is critically dependent on thereaction type (reduction, oxidation, and C-C bond formation)
* Recent findings on activation of C-H bonds, C-C bonds, and smallmolecules (C=O, HCN, RN=C, and CO2) and the latest developments onC-C bond reorganization, such as metathesis
* Advances in „chirally economical“ non-linear phenomena, racemiccatalysis, and autocatalysis
* Some of the recent discoveries that have led to a renaissance inthe field of organocatalysis, including the development of chiralBrönstead acids and Lewis acidic metals bearing the conjugatebase of the Brönstead acids as the ligands and the chiralbi-functional acid/base catalysts
The book ends with a thought-provoking perspective on the future ofasymmetric catalysis that addresses both the challenges and theunlimited potential in this burgeoning field. This is anauthoritative, up-to-date reference for organic chemists inacademia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also anexcellent textbook for graduate students studying advanced organicchemistry or chemical synthesis.