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![]( "Buchcover ISBN 9780470377789")
„The book is the first galectin book and contains a wealth ofinformation ... . The chapters provide researchers with a solidoverview of the state of the art in the various subjects and willbe useful to many galectin researchers.“ (ChemBioChem, January 2009)
„A comprehensive guide to the current understanding ofgalectins, their promising potential in drug design.“(Forbes, June 2008)
The comprehensive guide to the current understanding of galectinsand their promising potential in drug design
This is the first book focusing on galectins. It was inspired bytopics discussed at the symposium „Galectins: Structures, Functions, and Therapeutic Targets“ that was a part of the 234thAmerican Chemical Society meeting in 2007. To help chemists, biochemists, and others understand the challenges inherent in thestudy of galectins and build on recent advances in the field, theeditors have compiled articles from leading experts on galectinsand their biomedical applications. Galectins includes:
* An overview of early galectin research
* An explanation of the nature of galectins
* A discussion of the structure and functions of galectins, theirligand specificity and molecular mechanisms of action, and thelocalization of galectins in the cell
* An exploration of the roles galectins play in tumor growth andcancer, fibrosis, inflammation, and immunity
* A discussion of the effect of galectins on cell migration, angiogenesis, and chemoresistance
* An introduction to new approaches to designing galectininhibitors
This is the premier reference on galectins for organic, medicinal, carbohydrate, and pharmaceutical chemists, biochemists, molecularand cell biologists, pharmacologists, cancer researchers, andgraduate-level students in these disciplines, as well as cliniciansand drug developers.
This is the first book focusing on galectins. It was inspired bytopics discussed at the symposium „Galectins: Structures, Functions, and Therapeutic Targets“ that was a part of the 234thAmerican Chemical Society meeting in 2007. To help chemists, biochemists, and others understand the challenges inherent in thestudy of galectins and build on recent advances in the field, theeditors have compiled articles from leading experts on galectinsand their biomedical applications. Galectins includes:
* An overview of early galectin research
* An explanation of the nature of galectins
* A discussion of the structure and functions of galectins, theirligand specificity and molecular mechanisms of action, and thelocalization of galectins in the cell
* An exploration of the roles galectins play in tumor growth andcancer, fibrosis, inflammation, and immunity
* A discussion of the effect of galectins on cell migration, angiogenesis, and chemoresistance
* An introduction to new approaches to designing galectininhibitors
This is the premier reference on galectins for organic, medicinal, carbohydrate, and pharmaceutical chemists, biochemists, molecularand cell biologists, pharmacologists, cancer researchers, andgraduate-level students in these disciplines, as well as cliniciansand drug developers.
