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![]( "Buchcover ISBN 9780470626627")
„Mass Spectrometry in Sports Drug Testing is an excellenttextbook for anyone involved in the analytical characterization ofillicit substances and abused drugs.“ (Anal BioanalChem, 2011)
Mass Spectrometry in Sports Drug Testing
Characterization of Prohibited Substances and Doping Control Analytical Assays
von Mario ThevisEnables you to detect, identify, and characterize hundreds ofdrugs that may be used by athletes
Mass spectrometry has become essential to sports drug testing. This book examines both the principles of sports drug testing andthe use of mass spectrometry techniques and mass spectral data todetect, identify, and characterize hundreds of known and unknowndrugs that athletes may use to enhance their performance. Theauthor provides a detailed overview of the mass spectrometry ofnumerous classes of therapeutics and agents, various analyzers todetect low- and high-molecular weight drugs, as well as techniquesto discriminate between endogenously produced and syntheticallyderived compounds.
Mass Spectrometry in Sports Drug Testing begins with afull chapter dedicated to the history of sports drug testing. Next, the book provides the principles and techniques needed to maximizethe specificity and sensitivity of mass spectrometric assays, including:
* Detailed, step-by-step assays with sample preparation
* Discussion of both chromatographic separation and massspectrometric analysis
* Characterization of analytes in order to unequivocallyidentify banned substances
* Mass spectrometric behavior of low- and high-molecular weightanalytes
Throughout the book, descriptive examples illustrate theprinciples, advantages, and limitations of different assays.
Mass Spectrometry in Sports Drug Testing not only setsforth the role mass spectrometry plays in detecting drug use amongathletes, it also adds new insights into the health and ethicalissues of doping in sports.
Mass spectrometry has become essential to sports drug testing. This book examines both the principles of sports drug testing andthe use of mass spectrometry techniques and mass spectral data todetect, identify, and characterize hundreds of known and unknowndrugs that athletes may use to enhance their performance. Theauthor provides a detailed overview of the mass spectrometry ofnumerous classes of therapeutics and agents, various analyzers todetect low- and high-molecular weight drugs, as well as techniquesto discriminate between endogenously produced and syntheticallyderived compounds.
Mass Spectrometry in Sports Drug Testing begins with afull chapter dedicated to the history of sports drug testing. Next, the book provides the principles and techniques needed to maximizethe specificity and sensitivity of mass spectrometric assays, including:
* Detailed, step-by-step assays with sample preparation
* Discussion of both chromatographic separation and massspectrometric analysis
* Characterization of analytes in order to unequivocallyidentify banned substances
* Mass spectrometric behavior of low- and high-molecular weightanalytes
Throughout the book, descriptive examples illustrate theprinciples, advantages, and limitations of different assays.
Mass Spectrometry in Sports Drug Testing not only setsforth the role mass spectrometry plays in detecting drug use amongathletes, it also adds new insights into the health and ethicalissues of doping in sports.
