„For those wishing to gain an insight the potential power of toxicogenomics in toxicity assessment Toxicogenomics: A Powerful Tool for Toxicity Assessment will be if interest.“ (BTS Newsletter, Summer 2009)
Toxicogenomics is the integration of genomics to toxicology. Thistechnology is a powerful tool for collecting information from alarge number of biological samples simultaneously and thus it isvery useful for large-scale screening of potential toxicants.
Toxicogenomics: A Powerful Tool For Toxicity Assessmentprovides up-to-date state-of-the-art information presented by therecognized experts, and is therefore an authoritative source ofcurrent knowledge in this field of research. The potential linkbetween toxicology, genetics and human diseases makes this bookvery useful to investigators in many and varied disciplines ofscience and toxicology. Topics covered include:
* mechanistic toxicogenomics
* analysis and interpretation of toxicogenomic data
* principles of data mining in toxicogenomics
* design issues in toxicogenomics studies
* sources of variability in toxicogenomic assays
* Escherichia coli stress response as a tool for detectionof toxicity
* toxicogenomics as a tool to assess immunotoxicity
* toxicogenomics and ecogenomics for studying endocrinedisruption and basic biology
* use of toxicogenomics as an early predictive tool forhepatotoxicity
* nutrigenomics: the application of genomic signatures innutrition-related research
* application of toxicogenomics in drug discovery
* potential uses of toxicogenomic biomarkers in occupationalhealth and risk assessment
* usefulness of toxicogenomics in the regulatory environment
* perspectives on toxicogenomics at the US EnvironmentalProtection Agency
Toxicogenomics: A Powerful Tool For Toxicity Assessment is an essential resource for research scientists currentlyengaged in toxicogenomics, and will also be of interest toresearchers working in toxicology, genetics, medicine, pharmacology, and food sciences, and to regulators and riskassessors of drug, food, environmental and agriculturalproducts.
Toxicogenomics: A Powerful Tool For Toxicity Assessmentprovides up-to-date state-of-the-art information presented by therecognized experts, and is therefore an authoritative source ofcurrent knowledge in this field of research. The potential linkbetween toxicology, genetics and human diseases makes this bookvery useful to investigators in many and varied disciplines ofscience and toxicology. Topics covered include:
* mechanistic toxicogenomics
* analysis and interpretation of toxicogenomic data
* principles of data mining in toxicogenomics
* design issues in toxicogenomics studies
* sources of variability in toxicogenomic assays
* Escherichia coli stress response as a tool for detectionof toxicity
* toxicogenomics as a tool to assess immunotoxicity
* toxicogenomics and ecogenomics for studying endocrinedisruption and basic biology
* use of toxicogenomics as an early predictive tool forhepatotoxicity
* nutrigenomics: the application of genomic signatures innutrition-related research
* application of toxicogenomics in drug discovery
* potential uses of toxicogenomic biomarkers in occupationalhealth and risk assessment
* usefulness of toxicogenomics in the regulatory environment
* perspectives on toxicogenomics at the US EnvironmentalProtection Agency
Toxicogenomics: A Powerful Tool For Toxicity Assessment is an essential resource for research scientists currentlyengaged in toxicogenomics, and will also be of interest toresearchers working in toxicology, genetics, medicine, pharmacology, and food sciences, and to regulators and riskassessors of drug, food, environmental and agriculturalproducts.
