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„Principles of Cell Proliferation is a good background book for the study of eukaryotic cell proliferation. It will make a good companion for undergraduate courses on the subject... John K Heath writes in a very clear way that makes complicated concepts seem simple and this book is a good starting point in the mysteries of cell life and death.“ S J Araujo, Kings College London for the BSDB Newsletter, 2002
Principles of Cell Proliferation
von J. R. HeathControlled expansion of cell populations is a fundamental featureof living organisms, being a finely-tuned balance between cellproliferation and cell death. This book aims to explain themolecular mechanisms that lie behind the multiplication andsurvival of eukaryotic cells. This encompasses both the normalregulation of cell populations in development or physiologicaladaptation and pathological mechanisms of cell cycle control incancer.
Principles of Cell Proliferation progressively introducesthe function of growth factors, receptors, signal transductionpathways, gene expression and the conserved mechanisms of the cellcycle engine. This provides a context for understanding themechanistic consequences of the genetic alterations in oncogenesand tumour suppresser genes which underlie tumour formation. Thebook should satisfy advanced level courses in Cell Proliferation, Cell Cycle Control and Cancer Biology for biologists, biochemistsand medical students.
* * The book comes at a time when the underlying molecularmechanisms of cancer are beginning to be unravelled.
* Ideal for advanced level courses in Cell Proliferation, CellCycle or Cancer Biology.
* An accessible account of a subject many students findcomplex.
Principles of Cell Proliferation progressively introducesthe function of growth factors, receptors, signal transductionpathways, gene expression and the conserved mechanisms of the cellcycle engine. This provides a context for understanding themechanistic consequences of the genetic alterations in oncogenesand tumour suppresser genes which underlie tumour formation. Thebook should satisfy advanced level courses in Cell Proliferation, Cell Cycle Control and Cancer Biology for biologists, biochemistsand medical students.
* * The book comes at a time when the underlying molecularmechanisms of cancer are beginning to be unravelled.
* Ideal for advanced level courses in Cell Proliferation, CellCycle or Cancer Biology.
* An accessible account of a subject many students findcomplex.