„... an excellent source of information... provides avaluable insight into the present and future strategies for boneand tissue engineering.“ (Annals of Biomedical Engineering, February 2004)
„... an excellent source of information... providesvaluable insight into the present and future strategies for boneand tissue engineering“ (Annals of Biomedical Engineering, Issue 32:02)
„... I found this book to be an excellent publication forresearchers already engaged in the field of tissue engineering“.(The Biochemist, 10 July 2003)
„... successfully sets about translating bone andcartilage tissue engineering principles into a clinically relevantscience...“ (The Newsletter of the British Society ofCell Biology, Summer 2005)
Tissue engineering takes advantages of the combined use of culturedliving cells and three-dimensional scaffolds to reconstruct adulttissues that are absent or malfunctioning. This book bringstogether scientists and clinicians working on a variety ofapproaches for regenerating of damaged or lost cartilage and boneto assess the progress of this dynamic field.
In its early days, tissue engineering was driven by materialscientists who designed novel bio-resorbable scaffolds on which toseed cells and grow tissues. This ground-breaking work generatedhigh expectations, but there have been significant stumbling blocksholding back the widespread use of these techniques in the clinic. These challenges, and potential ways of overcoming them, are giventhorough coverage in the discussions that follow eachchapter.
The key questions addressed in this book include the following. Howgood must cartilage repair be for it to be worthwhile? What is thebest source of cells for tissue engineering of both bone andcartilage? Which are the most effective cell scaffolds? What arethe best preclinical models for these technologies? And when itcomes to clinical trials, what sort of outcome measures should beused? With contributions from some of the leading experts in thisfield, this timely publication will prove essential reading foranyone with an interest in the field of tissue engineering.
In its early days, tissue engineering was driven by materialscientists who designed novel bio-resorbable scaffolds on which toseed cells and grow tissues. This ground-breaking work generatedhigh expectations, but there have been significant stumbling blocksholding back the widespread use of these techniques in the clinic. These challenges, and potential ways of overcoming them, are giventhorough coverage in the discussions that follow eachchapter.
The key questions addressed in this book include the following. Howgood must cartilage repair be for it to be worthwhile? What is thebest source of cells for tissue engineering of both bone andcartilage? Which are the most effective cell scaffolds? What arethe best preclinical models for these technologies? And when itcomes to clinical trials, what sort of outcome measures should beused? With contributions from some of the leading experts in thisfield, this timely publication will prove essential reading foranyone with an interest in the field of tissue engineering.
