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Buchcover - Predictive Approaches in Drug Discovery and Development - ISBN 978-1-118-23025-1
„The ability to correlate in vitro and in vivo biomarkerinformation in the process of drug discovery and development liesat the heart of translational research. The goal is to rapidlytranslate basic discoveries into clinical applications. This bookprovides state-of-the-art information on this exciting new researchapproach.“ (Doody's, 8 February 2013)
„The text is packed with interesting, comprehensive, andpertinent information, clearly presented with salient pointsreinforced by inclusion in text boxes . . . This is an admirabletextbook for those dealing with drug discovery and development. Ienjoyed reading through it and I would recommend it to anyone whohas an interest, or is developing an interest, in the field ofbiomarkers and their, as yet, unfulfilled potential.“ (ISSX International Society for the Study of Xenobiotics, 1December 2012)
Predictive Approaches in Drug Discovery and Development
Biomarkers and In Vitro / In Vivo Correlations
herausgegeben von J. Andrew Williams, Richard Lalonde, Jeffrey R. Koup und David D. ChristPractical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.
