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„The book serves as a valuable desk reference volume and describes well the key concepts of the standard and emerging enzyme technologies that together constitute some of the fundamental principles and knowledge on which drug discovery research is based.“ (ChemMedChem, 1 August 2015)
Enzyme Technologies
Pluripotent Players in Discovering Therapeutic Agent
von Hsiu-Chiung Yang, Wu-Kuang Yeh und J. R. McCarthySets the stage for advances in drug discovery using thelatest enzyme technology
Reviewing new and emerging applications of enzyme technology indrug discovery, this book highlights some of the most promisingareas of pharmaceutical and biotechnology research. It coversenzyme assay technology, utilization of enzymology for prodrugdesign, and the application of enzymes as therapeutic agents. Expert reviews highlight how our latest understanding of enzymologyis used to develop new practical applications in drug discovery anddesign.
Filled with case studies, Enzyme Technologies: PluripotentPlayers in Discovering Therapeutic Agents enables readers tobetter understand the diverse functions of enzymes and masterspecific applications in drug discovery research. In addition tosmall molecule drug discovery, the book explores new developmentsin enzymes as therapeutic agents for genetic disorders.
* Section A, Enzymes - Essential Workhorses inPharmaceutical Research, offers support in selecting the bestenzyme targets for drug discovery, designing enzyme inhibitors fortherapeutic agents, and evaluating selective enzymeinhibitors.
* Section B, Enzymes - Indispensable Tools for ImprovingDruggability, sets forth the principles alongside real-worldexamples of exploiting specific properties of enzymes to designsuccessful prodrugs.
* Section C, Enzymes - Powerful Weapons for CorrectingNature's Errors, provides new insights on applying enzymes astherapeutic agents or diagnostic tools to treat geneticdisorders.
Chapters are contributed by leading experts from around theworld. Their contributions are based on a thorough review of thecurrent literature as well as their own research.
Reviewing our latest understanding of the nature of enzymes andtheir role in drug discovery, this book is recommended forresearchers in pharmaceuticals and biotechnology as well as forresearchers in enzymology, biochemistry, molecular biology, andmedicinal chemistry.
Reviewing new and emerging applications of enzyme technology indrug discovery, this book highlights some of the most promisingareas of pharmaceutical and biotechnology research. It coversenzyme assay technology, utilization of enzymology for prodrugdesign, and the application of enzymes as therapeutic agents. Expert reviews highlight how our latest understanding of enzymologyis used to develop new practical applications in drug discovery anddesign.
Filled with case studies, Enzyme Technologies: PluripotentPlayers in Discovering Therapeutic Agents enables readers tobetter understand the diverse functions of enzymes and masterspecific applications in drug discovery research. In addition tosmall molecule drug discovery, the book explores new developmentsin enzymes as therapeutic agents for genetic disorders.
* Section A, Enzymes - Essential Workhorses inPharmaceutical Research, offers support in selecting the bestenzyme targets for drug discovery, designing enzyme inhibitors fortherapeutic agents, and evaluating selective enzymeinhibitors.
* Section B, Enzymes - Indispensable Tools for ImprovingDruggability, sets forth the principles alongside real-worldexamples of exploiting specific properties of enzymes to designsuccessful prodrugs.
* Section C, Enzymes - Powerful Weapons for CorrectingNature's Errors, provides new insights on applying enzymes astherapeutic agents or diagnostic tools to treat geneticdisorders.
Chapters are contributed by leading experts from around theworld. Their contributions are based on a thorough review of thecurrent literature as well as their own research.
Reviewing our latest understanding of the nature of enzymes andtheir role in drug discovery, this book is recommended forresearchers in pharmaceuticals and biotechnology as well as forresearchers in enzymology, biochemistry, molecular biology, andmedicinal chemistry.
