Plasminogen: Structure, Activation, and Regulation

herausgegeben von David M. Waisman

I. Plasminogen: Structure and Regulation.
1. Human Plasminogen: Structure, Activation, and Function.
2. Plasminogen Activators: Structure and Function.
3. Plasminogen Activators Inhibitors.
4. Regulation of Plasminogen Gene Expression.
5. Plasminogen Receptors.
6. The Role of Lys-Plasminogen in Cell-Mediated Plasmin Production.
7. Plasmin Reductase.
8. Mechanism of Angiostatin Formation from Plasminogen.
II. Physiological Roles of Plasminogen.
9. Lessons Learned from the Pig Deficient Mice (Plg—/—).
10. Plasminogen-Directed Phenotypes in Mice.
11. Role of the Plasminogen and MMP Systems in Wound Healing.
12. Matrix Metalloproteinases and the Plasminogen System in Tumor Progression.
13. Role of Plasminogen Activation in Hematopoietic Malignancies and in Normal Hematopoiesis.
14. The Role of Plasminogen in Bone Remodeling.
15. Plasminogen Activators in CNS Physiology and Disease.
16. Role of the Plasminogen Activator-Plasmin System in Angiogenesis.