Science of Synthesis: C-1 Building Blocks in Organic Synthesis Vol. 2
Alkenations, Cross Couplings, Insertions, Substitutions, and Halomethylations
herausgegeben von Piet W.N.M. van LeeuwenThe two-volume set on C-1 Building Blocks in Organic
Synthesis critically reviews the state of the art of a wide variety of reactions
by which one carbon atom is added to an organic molecule, forming a C-C bond. In
spite of the numerous classic reactions of this kind, there has been enormous
progress in recent years, especially for those reactions involving catalytic
methods. Introduction of substituted methyl groups is a major challenge and only
very recently the first catalysts have been discovered that enable the
introduction of fluoromethyl groups in aromatics.
Synthesis critically reviews the state of the art of a wide variety of reactions
by which one carbon atom is added to an organic molecule, forming a C-C bond. In
spite of the numerous classic reactions of this kind, there has been enormous
progress in recent years, especially for those reactions involving catalytic
methods. Introduction of substituted methyl groups is a major challenge and only
very recently the first catalysts have been discovered that enable the
introduction of fluoromethyl groups in aromatics.