Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders

Inhaltsverzeichnis

• The Role of ?-Synuclein in Parkinson’s Disease: A Biophysical Analogy to A? and Alzheimer’s Disease.
• Purification of Lewy Bodies and Identification of ? -Synuclein as a Major Component of Lewy Bodies.
• Mutational Analysis of Tau in Chromosome 17-Linked Dementia.
• Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.
• Tau Mutations: Genetics and Pathogenetic Mechanisms.
• Tauopathies and ?-Synucleinopathies.
• Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.
• Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.
• Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.