Leukemia Cell Biology: Cytogenetics.- Chromosome Translocations Play a Key Role in Leukemogenesis with an Introduction by F. Lampert.- Fifty-nine Cases of Acute Myeloid Leukemia with Inversion inv(16)(pl3q22): Do Additional Chromosomal Aberrations Influence Prognosis?.- Chromosome Abnormalities and Karyotype Evolution in the Stem Cell Compartments of AML and MDS.- Karyotypic Abnormalities in Secondary Leukemia of Children.- Deletion of Chromosome 6p as Primary Karyotypic Anomaly in Secondary Acute Nonlymphocytic Leukemia.- Molecular Cytogenetic Analysis of 7q Abnormalities in Acute Leukemia.- Unusual Karyotype 46, XX, inv(8)(p21q24), del(20)(q11q13) in a Case of Acute Leukemia M6 in a Child.- Acute Myeloblastic Leukemia M2 with the 8;12 Translocation Associated with Granulocytic Sarcoma.- Cytogenetic Subgroups in Childhood Acute Myeloblastic Leukemia at the Schneider Children’s Medical Center of Israel.- FISH Analysis in Acute Leukemia with Initially Abnormal Karyotypes and Normal Karyotypes in Relapse.- Cytogenetic Findings of Acute Leukemias in the Ukraine.- Detection of Minimal Tumor Cell Populations by FICTION.- Leukemia Cell Biology: Molecular Biology.- A Cloning Strategy to Identify Genes that Functionally Interact with Bcr-Abl for Transformation.- Biology and Detection of t(4;11) Leukemias.- Homozygous Deletion of the p16 Gene in Childhood Acute Lymphoblastic Leukemia.- CDKN2 Deletions in Leukemia-Derived Cell Lines: Detection by Fluorescence In Situ Hybridization with Interphase Cells.- Diversity of the TcR-d Gene Rearrangements Indicates Subclone Formation in Acute B Cell Precursor Leukemias.- Molecular Genetic Detection of Chromosomal Abnormalities at 11q23 in Patients with De Novo and Secondary Acute Leukemia.- Sequence Analysis of the GAP-Related Domain of the NF1-Gene and All Three RAS Protooncogenes in Patients with Secondary Acute Leukemia.- Molecular Genetic Screening of Children with Acute Leukemia by RT-PCR.- Detection of the Wilms Tumor Gene (wt-1) mRNA in Complete Remission of AML Frequently Precedes Relapse.- CBF? MYH11 Rearrangement in M4Eo with Inversion 16: A Novel Marker for Diagnosis of Minimal Residual Disease by RT-PCR.- Detection of Minimal Residual Disease on Bone Marrow Smears by Reverse Transcriptase Polymerase Chain Reaction.- Evaluation of Chimerism After Allogeneic Bone Marrow Transplantation Using Amplification of Hypervariable Regions of Human Genome by Polymerase Chain Reaction.- Leukemia Cell Biology: Cytokines.- Truncated Granulocyte-Colony Stimulating Factor Receptors in Severe Congenital Neutropenia Terminating in Acute Myeloid Leukemia.- BCR/ABL and Signal Transduction Pathways.- Interleukins (IL-1, IL-2, IL-4, IL-6) and TNF Production in Children with Acute Lymphoblastic Leukemia.- Insulin-Like Growth Factors and Their Specific Binding Proteins in Leukemia (ALL) and Non-Hodgkin Lymphoma.- IFN-? is an Inhibitory Cytokine of Leukemic B-Cell Precursors.- Cytokine Serum Levels During the Course of Acute Myeloid Leukemia.- Expression of FLT3 and FLT3 Ligand in Human Leukemia-Lymphoma Cell Lines.- GM-CSF Dose Response Curves in Priming of AML Progenitors for Ara-C.- Different Potential of G-CSF, GM-CSF, and pIXY in Priming of Myeloid Leukemic Progenitors for Ara-C.- Leukemia Cell Biology.- An Alternative Transcript of the Human GM-CSF Receptor Alpha Chain Lacking the Signal Sequence is Found in AML Blasts and Normal Controls.- Marked Effect of the Combination of a Novel Vitamin D3 Analog, KH 1060, and 9-cis-RA on Inhibition of Clonal Growth, Decrease of bcl-2 Level and Induction of Apoptosis in HL-60 Cells.- Adoptive Transfer of NK Cells Can Eradicate Residual Leukemia After BMT.- Characterization of Normal and Leukemic Lymphohematopoietic Precursor Cells by Three-Color Flow Cytometry and Detection of Clone-Specific Leukemia-Associated T-Cell Receptor ? Rearrangements.- Monitoring Leukemic Cells During the Course of Acute Leukemia by Immunphenotyping and Genotyping.- Flowcytometric Detection of Aneuploidies in Acute Lymphoblastic Leukemia (ALL) Before and After Chemotherapy.- Comparison of Growth Patterns of Acute Myeloid Leukemia Cells In Vitro and In Vivo by Flow Cytometry.- The Influence of Short Term Liquid Culture of Leukemic Blasts on Their Phenotype.- Correlation of Deoxycytidine Deaminase, Thymidine Kinase and Polymerase Alpha Activity and Deoxycytidine Deaminase Gene Expression In Vivo with Clinical Response to TAD-9+GM-CSF Induction Therapy in Acute Myeloid Leukemia.- CD7+CD4-CD8-Blast Cells in Acute Leukemia.- Lymphoid Antigen Expression in Acute Myeloid Leukemia.- CD54 Expression and Its Role in Homotypic Aggregation of the Blasts of Acute Myeloblastic (AML) and Acute Lymphoblastic Leukemia (ALL).- Adhesion Molecule Receptor Profile in Acute Leukemia.- Expression of Adhesion Molecules on Blood Derived CD34 Positive Cells Immediately After Thawing and After Ex Vivo Incubation with Cytokines.- Cytomorphology and Clinical Outcome in 80 Patients with AML M4Eo and Inversion 16.- Prognostic Relevance of Proteolytically Inactivated Alpha1-Antitrypsin Excreted in the Urine of Patients with Acute Myeloid Leukemia.- Studies on Plasma Coagulation in Children with ALL Undergoing Therapy Using the COALL-05-92 Protocol.- Residual Leukemia.- Methods for Detection of Minimal Residual Disease.- Molecular Biological Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia.- Immunophenotypic Detection of Minimal Residual Disease in Acute Lymphoblastic Leukemia.- Molecular Biological Detection of Minimal Residual Disease in Acute Myeloid Leukemia.- Detection on Minimal Residual Disease in Cytogenetically Defined Prognostic Subgroups of AML.- New Strategies: Nucleoside Analogs.- Current Approaches in the Treatment of Chronic Lymphocytic Leukemia.- Fludarabine for the Treatment of Advanced Chronic Lymphocytic Leukemia: Results of a Prospective Randomized Comparison with Cyclophosphamide, Doxorubicin, and Prednisone.- Potential Immunological Action of Purine Nucleoside Analogs.- Fludarabine and Fludarabine, Mitoxantrone, Dexamethasone in the Management of Low-Grade Non-Hodgkin Lymphomas.- Fludarabine in Low-Grade Lymphoma: St. Bartholomew’s Hospital Experience.- Future Role of Purine Analogues in Oncology.- New Strategies: Idarubicin.- Intracellular Effects of Anthracyclines: Distribution, DNA-Binding and Genotoxicity.- Specific Role of Idarubicin During Induction Therapy of Childhood Acute Myeloblastic Leukemia.- Overview of Current Treatment for Acute Myeloid Leukemia.- Chemotherapy for Acute Myeloid Leukemia: the State of the Art and the Contribution of Idarubicin.- Phase II Trial of Idarubicin, Fludarabine, Cytosdine Arabinoside and Filgrastim (G-CSF) for Treatment of Refractory, Relapsed, and Secondary Acute Myeloid Leukemia.- New Strategies Using Growth Factors: G-CSF.- Mechanisms of Regulated Drug Sensitivity.- Current Status of Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor in the Management of Acute Lymphoblastic Leukemia.- Peripheral Blood Stem Cell Transplantation in Acute Myeloid Leukemia.- New Strategies Using Growth Factors: GM-CSF, PIXY 321.- Growth Factors in AML: Updates.- Granulocyte-Macrophage Colony-Stimulating Factor-Based Priming Concepts in Acute Myeloid Leukemia.- Cancer and Leukemia Group B Studies with Hematopoietic Growth Factors in Patients with Acute Myeloid Leukemia.- Preclinical Evaluation of Granulocyte-Macrophage Colony-Stimulating Factor/Interleukin 3 Fusion Protein (PIXY 321) in Acute Myeloid Leukemic Cells.- Initial Trial of PIXY 321 Following Autologous Bone Marrow Transplantation.- New Strategies: Antifungal Treatment.- Fluconazole Prophylaxis of Invasive Fungal Infections During Intensive Chemotherapy for Relapsed Acute Myeloid Leukemia: Interim Analysis of a Randomized Multicenter Trial.- Current Approaches in the Prevention of Invasive Aspergillosis.- Early Empiric Antifungal Treatment of Infections in Neutropenic Patients Comparing Fluconazole with Amphotericin B/5-Flucytosine.- Pharmacology.- Dependence of Asparaginase-Induced Coagulopathy on Serum Asparaginase Activity: A Randomized Trial.- Significant Differences in the Pharmacokinetics of two l-Asparaginase Preparations from Escherichia coli.- Pharmacokinetic/Pharmacodynamic Monitoring of l-Asparaginase in Children.- Asparaginase Activities In Vitro Are Highly Sensitive to Different Buffer Conditions.- Influence of l-Asparaginase Escherichia coli and Erwinia on Antithrombin III and Coagulation Factors During Induction Therapy of Acute Lymphoblastic Leukemia in Children.- Infusion Rate Does Not Influence Ifosfamide Side-Chain Metabolism.- Busulfan Pharmacology in Bone Marrow Transplantation Patients.- Topoisomerase II Activities in Human Leukemic Cells and Their Sensitivity to Anthracyclines and Podophyllotoxines.- Quantitative Cytosine Arabinoside Metabolism in HL60 and Raji Cells Using a Novel High Performance Liquid Chromatography Assay for Detection and Quantitation of 3H-Cytosine Arabinoside and Its Metabolites.- Role of Deoxycytidine Triphosphate for Feedback Regulation of Deoxycytidine Kinase and Phosphorylation of Cytosine Arabinoside in Whole Leukemic Cells.- Drug Resistance Profile: Strongest Independent Prognostic Factor in Childhood Acute Lymphoblastic Leukemia in a BFM-Oriented Treatment Protocol.- In Vitro Drug Sensitivity of Acute Myeloid Leukemic Cells Using the Methyl-Thiazol-Tetrazolium Assay.- Does P-Glycoprotein Predict Response to Chemotherapy? Expression of P-Glycoprotein in Children’s and Adults’ Leukemia -Correlation with Clinical Outcome.- Clinical Relevance of P-Glycoprotein-Related Resistance in Patients with Acute Leukemia.- Lack of Correlation Between Multi-Drug Resistance Expression and Clinical Response to Chemotherapy in Patients with Acute Myeloid Leukemia.- Coexpression of mdr-1 and myc Genes in Relation to Prognosis in Acute Leukemia Patients.- ALL in Children.- Risk Adapted Treatment in Childhood Acute Lymphoblastic Leukemia: Data from the Berlin-Frankfurt-Münster Group.- Mechanisms of Treatment Failure in Childhood Acute Lymphoblastic Leukemia: Children’s Cancer Group Initiatives.- Risk-Adapted Treatment for Acute Lymphoblastic Leukemia: Findings from St. Jude Children’s Research Hospital.- Risk-Adapted Therapy for Acute Lymphocytic Leukemia: The Pediatric Oncology Group Experience.- Treatment Results in Childhood B Non-Hodgkin Lymphoma with a Modified BFM Protocol in St. Petersburg.- Similar Outcome in Boys with Isolated and Combined Testicular Acute Lymphoblastic Leukemia Relapse After Stratified BFM Salvage Therapy.- Acute Cholecystitis Complicating Intensive Chemotherapy of Chilhood Acute Lymphoblastic Leukemia.- Prognostic Significance of Peanut Agglutinin Binding in Childhood T-Cell Acute Lymphoblastic Leukemia.- Longitudinal Study of Cognitive, Motor, and Behavioral Functioning in Children Diagnosed with Acute Lymphoblastic Leukemia: A Report of Early Findings from the Childrens Cancer Group.- ALL in Adults.- Treatment of Biologically Determined Subsets of Acute Lymphoblastic Leukemia in Adults: Cancer and Leukemia Group B Studies.- Treatment of Acute Lymphoblastic Leukemia in the Elderly: Results of the GIMEMA 0288 > 60 Years Trial.- Allogeneic and Autologous Bone Marrow Transplantation and Chemotherapy in First Remission of Adult Acute Lymphoblastic Leukemia: Results of the LALA 87 Trial of the French Group.- Bone Marrow Transplantation Versus Chemotherapy in Acute Lymphoblastic Leukemia. Joint Trial of the Medical Research Council (UKALL-12) with the United States Eastern Cooperative Oncology Group E2993.- Bone Marrow Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.- AML in Children.- Childrens Cancer Group Studies in Acute Myeloid Leukemia, 1979-1995: Three Strategies That Have Worked.- Intensified Early Therapy for Childhood Acute Myeloid Leukemia: Pilot Studies of the AIEOP Cooperative Group.- A Randomized Comparative Study of Purged Autologous Bone Marrow Transplantation Versus Intensive Multiagent Consolidation Chemotherapy in First Remission of Acute Myeloid Leukemia in Children (Pediatric Oncology Group Study—POG 8821).- Prognostic Factors and Treatment in Pediatric Acute Myeloblastic Leukemia: French Trials.- Childhood Acute Nonlymphoblastic Leukemia - Results of the Austrian-Hungarian Acute Myeloid Leukemia Studies IGCI-84 and 90.- Results of Intensive Chemotherapy of Acute Myeloid Leukemia in Children According to the Berlin-Frankfurt-Münster Strategy: A Single Institution Trial.- Down’s Syndrome and Megakaryoblastic Leukemia.- AML in Adults.- Therapeutic and Prognostic Factors in the Management of Acute Myeloid Leukemia.- Prognostic Factor Analyses in Acute Myeloid Leukemia: M. D. Anderson Experience.- Intensified Therapy of Acute Myeloid Leukemia: Results of the German AML Cooperative Group.- Intensified Induction Therapy in Acute Myeloid Leukemia.- Results of All-Trans Retinoic Acid Treatment in Acute Promyelocytic Leukemia (European Experience).- Intensified Post-Remission Chemotherapy for Adults with Acute Myeloid Leukemia: An Update of CALGB 8525.- Postremission Therapy: The Role of Allogeneic Bone Marrow Transplantation in Acute Myelogenous Leukemia: An Analysis of the AML8A EORTC-GIMEMA Protocol.- Impact of Marrow Transplantation in Acute Myeloid Leukemia in First Complete Remission: Experience from MRC AML-10 Trial.- Bone Marrow Transplantation for Acute Myelogenous Leukemia.- Autologous Bone Marrow Transplantation Versus Chemotherapy in Acute Myeloblastic Leukemia Patients. Argentinean Study Results.- Granulocyte-Macrophage Colony-Stimulating Factor in the Therapy of Adults with De Novo Acute Myeloblastic Leukemia: An Update of a Double-Blind Randomized, Placebo-Controlled Trial.- Longterm Follow Up of a Prospective Multicenter Trial with a High-Dose Cytosine Arabinoside and Daunorubicin Postremission Therapy in Adults with De Novo Acute Myeloid Leukemia.- Idarubicin, Cytorabine, Etoposide Versus Risk-Adjusted Daunorubicin Plus Cytosine Arabinoside for Induction Treatment of Acute Myeloid Leukemia: A Randomized Multicenter Trial.- “7+3” Versus “7+3+VP-16” as Remission Induction in Acute Myeloid Leukemia Patients Under the Age of Sixty Years: Preliminary Results of a Russian Multicenter Trial.- Poor Risk Acute Myelogenous Leukemia Patients Undergoing the Fludarabine-Cytosine Arabinoside-Filgrastim Regimen: Multidrug Resistance Expression, Granulocyte Colony-Stimulating Factor Priming Activity and Clinical Response.- Granulocyte-Macrophage Colony-Stimulating Factor During and After Remission Induction Treatment for Elderly Patients with Acute Myeloid Leukemia.- Prospective Comparison of Allogeneic Bone Marrow Transplantation, Intensive Consolidation Chemotherapy, and Unpurged Autologous Bone Marrow Transplantation as Post-Remission Therapy in Adult Acute Myeloid Leukemia.- Late Relapses in Adult Acute Myelogenous Leukemia: A Retrospective Study of Characteristics and Outcome in 76 Cases.- Methods to Detect Prognostic Factors in Acute Myeloid Leukemia.- Idarubicin or Mitoxantrone, VP-16, and Cytarabine for Induction/Consolidation Therapy Followed by Autologous Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia: A Feasibility Study.- High-Dose Chemotherapy with Busulfan, Cyclophosphamide and VP 16 as Conditioning for Allogeneic and Autologous Bone Marrow Transplantation for Patients with Acute Myeloid Leukemia.- YNK01, an Oral Cytosine Arabinoside Derivative in Acute Myeloid Leukemia and Chronic Myeloid Leukemia.- Secondary Leukemia, Myelodysplastic Syndrome.- Genetic Instability and Evolution of Karyotype in Secondary Acute Myeloid Leukemia.- Prognostic Value of Dysmyelopoiesis in 128 Patients with De Novo Acute Myeloid Leukemia.- Incidence of Secondary Leukemias After Therapy of Childhood Hodgkin’s Disease Without Nitrogen-Mustard. Results of the German-Austrian Study Group.- Intensive Therapy of Myelodysplastic Syndromes and Secondary Leukemias: Preliminary Findings of the French Experience.- Preliminary Results of a Placebo-Controlled, Double-Blind Trial Evaluating Sequential HD-AraC/Mitoxantrone Induction Chemotherapy with or Without Granulocyte-Macrophage Colony-Stimulating Factor in Patients with High-Risk Myelodysplastic Syndromes.- Childhood Myelodysplastic Syndromes Treated with Acute Myeloid Leukemia Regimens.- Remission Rates, Survival and Prognostic Factors in Ninety Patients with Advanced Myelodysplastic Syndromes Treated with Intensive Chemotherapy.- Secondary Myelodysplastic Syndromes: Morphological Findings, Cytogenetics, and Clinical Course in 55 Patients.- Myelodysplastic Syndromes or Leukemia Following MDS Treated with Allogeneic Bone Marrow Transplantation: A Survey of the Working Party on Chronic Leukemia of the European Cooperative Group for Blood and Marrow Transplantation.- Cyclosporin A in the Treatment of Myelodysplastic Syndrome.- Supportive Care.- Mediators in Sepsis and Septic Shock.- Interventional Antimicrobial Strategy in Neutropenic Infections.- Acyclovir and Cytomegalovirus Immunoglobulins as Prophylaxis for Cytomegalovirus Infections in Allogeneic Bone Marrow Transplant Recipients.- Challenge of Alloimmunization and Refractoriness to Platelet Transfusion.- Polymerase Chain Reaction for Detection of Various Aspergillus Species in Clinical Samples.- Screening with Sensitive Detection Methods Allows a Reduction in the Incidence of Cytomegalovirus Disease After Allogeneic Bone Marrow Transplantation.- Therapy of Sepsis Syndrome with Human Polyclonal IgM-Enriched Immunoglobulins: Interim Analysis of a Randomized Trial in Neutropenic Cancer Patients.- The 10/NL Trigger for Prophylactic Platelet Transfusion in Acute Myeloid Leukemia: A Prospective Comparative Multicenter Study.- Transplantation of Allogeneic Peripheral Blood Progenitor Cells Alone or in Addition to Bone Marrow.- Quality of Life in Patients with Acute Myeloid Leukemia -A Longitudinal Study.